Optimized second-generation CRY2–CIB dimerizers and photoactivatable Cre recombinase
نویسندگان
چکیده
منابع مشابه
Optimized second generation CRY2/CIB dimerizers and photoactivatable Cre recombinase
Arabidopsis thaliana cryptochrome 2 (AtCRY2), a light-sensitive photosensory protein, was previously adapted for use in controlling protein-protein interactions through light-dependent binding to a partner protein, CIB1. While the existing CRY2-CIB dimerization system has been used extensively for optogenetic applications, some limitations exist. Here, we set out to optimize function of the CRY...
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ژورنال
عنوان ژورنال: Nature Chemical Biology
سال: 2016
ISSN: 1552-4450,1552-4469
DOI: 10.1038/nchembio.2063